Back to top
Nucleic Acid Isolation
It is well known in the scientific world that the purity and integrity of the isolated DNA/RNA has a significant impact on the final outcome of downstream genomic analysis.
Therefore, it is of paramount importance to rely on optimized and well-proven isolation systems when performing any kind of genomic analysis.
Microsynth looks back on more than 15 years of experience in DNA/RNA isolation from different and difficult matrices like plant material, soil, food or stool.
Therefore, it is of paramount importance to rely on optimized and well-proven isolation systems when performing any kind of genomic analysis.
Microsynth looks back on more than 15 years of experience in DNA/RNA isolation from different and difficult matrices like plant material, soil, food or stool.
Features and Benefits
Experienced and Imaginative
Microsynth has extensive experience with the isolation of nucleic acids from various sample matrixes. Isolation protocols are thoroughly tested and validated before the actual samples are processed. If necessary and depending on your sample new protocols are compiled de novo.
Cost-Effective
Profit from our experience. Improve your overall productivity by spending more time evolving your experiments and analyzing your data rather than expending time and effort on optimizing your DNA/RNA isolation approach.
Convenient
One-stop solution. Let Microsynth plan and execute your whole project. From sampling, over nucleic acid isolation to a broad portfolio of genomic analyses you can get everything from one source.
One-stop solution. Let Microsynth plan and execute your whole project. From sampling, over nucleic acid isolation to a broad portfolio of genomic analyses you can get everything from one source.
Fast
Using our automated isolation methods and critical know-how we are able to process your samples fast and efficient.
Using our automated isolation methods and critical know-how we are able to process your samples fast and efficient.
Technical Support
Direct access to support by experienced academic staff from Monday – Friday.
Direct access to support by experienced academic staff from Monday – Friday.
Sample Matrices
Microsynth is able to process a large variety of sample matrices and DNA/RNA sources. Our well-proven and validated protocols for nucleic acid isolation ensure that the following 4 steps are professionally handled:
- Effective disruption of the cellular structure to generate a lysate
- Clean separation of the soluble nucleic acids from cell debris and other insoluble materials
- Separation of nucleic acids from soluble proteins
- Final high-level purification of nucleic acids
| Sample Matrix | Description |
| Industry Products | |
| Organic and Inorganic Chemical Products | Powders, liquids, gels, complex and demanding chemical composition |
| Biotechnological Products | Robust validated methods fit for purpose |
| Drug Products | Lipid nanoparticles, various biotechnological products for residual DNA testing |
| Viral Vectors | Single stranded or double stranded DNA or RNA viruses |
| Biological Fluids, Cells and Solid tissues | |
| Cell Culture | Animal, supernatants (viral), research cell banks, master cell banks, working cell banks |
| Animal Soft Tissues & Cells | Liver, brain, lung, heart, kindney, spleen |
| Animal Hard Tissues | Bones, teeth, shells |
| Animal Integumentary System | Feathers, hair, fin, exuviae |
| Body Fluids | Blood, lymphocytes, plasma, urine, mucus, cerebrospinal fluid, saliva |
| Fixed Tissues | FFPE and glass-slide samples |
| Medical Samples | Ichor, collections and biobanks |
| Tough to Lyse | |
| Plants and Seeds | Fresh, dried and herbarial samples, wood splints, roots |
| Fungi | Mycelium, fruiting body |
| Culture | Fungal, bacterial, archeal, supernatants (phage) |
| Environmental (Free) Samples | Biofilm, fecal, scat, soil (clay, loam, aquifer sediments, potting soil, sand, sewer slugde, manure, compost, marine sediments), water |
| Plasmid DNA Purification | |
| E.coli | Mini-, Midi-, Maxi-, Gigaprepscales / BAC, YAC, PAC plasmid |
| Yeast | Miniprepscale |
You don't find your sample type on our list?
Please contact us and we will find out how we can help you.
Added Services
Complex Matrices
You have unusual volumes, shapes, matrices, origins or consistence?
Most probably we have already worked with such samples and developed a standardized isolation protocol.
If not, we will be able to develop a an individual approach.
If not, we will be able to develop a an individual approach.
Sampling/Sample Tracking
To simplify your sampling procedure, we can supply you with the transport vials, transport buffers and containers.
To simplify your sampling procedure, we can supply you with the transport vials, transport buffers and containers.
Precise sample tracking with a barcoding system is possible.
For certain project we can assist your field sampling.
Examples of complex samples and sample tracking we have already worked with:
For certain project we can assist your field sampling.
Examples of complex samples and sample tracking we have already worked with:
- High volume liquid samples: water drain samples, environmental aquatic samples (300ml – 1l and more), blood
- DNA isolation from ash, different kind of soil, stool, scat, biofilm
- Delivery of the suitable transport vials, transport buffers to the customer
- Setup and running of a barcoding system
- Assistance in field sampling
Project Outsourcing
Sample processing and DNA/RNA isolation is often a part of larger and more complex research projects. Microsynth has gathered years of work experience in planning and successfully completing such projects. With the combined knowledge of our different business units we are prepared to manage and realize a plurality of molecular biology projects.
Get in contact with us to see how we can enrich your research.